Open AccessNew generation oral anticoagulant apixaban enhances embryo implantation by increasing integrin ß3 expression in rats: A pilot study
Author(s) -
Şule Yıldırım Köpük,
Nida Özer,
Yasemin Çekmez,
Aslı Çakır,
Kiran Grover
Publication year - 2021
Publication title -
jbra
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 14
eISSN - 1518-0557
pISSN - 1517-5693
DOI - 10.5935/1518-0557.20210122
Subject(s) - apixaban , oral anticoagulant , embryo , integrin , andrology , anticoagulant , pharmacology , medicine , microbiology and biotechnology , biology , rivaroxaban , receptor , atrial fibrillation , warfarin
The first aim of this study was to investigate the effect of apixaban on endometrial receptivity via immunohistochemical investigation of integrin β3 expression in pregnant rats. The second aim was to compare the endometrial effects of both subcutaneous and oral anticoagulant drugs in terms of integrin β3 expressions.