Open Accessp63 expression in granulosa-luteinized cells of infertile patients with peritoneal endometriosis submitted to in vitro fertilization
Author(s) -
Joelmir José Chiesa,
Silvia Liliana Cossio,
Emily de Conto,
Vanessa Krebs Genro,
João Sabino Cunha-Filho
Publication year - 2021
Publication title -
jbra
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 14
eISSN - 1518-0557
pISSN - 1517-5693
DOI - 10.5935/1518-0557.20210090
Subject(s) - endometriosis , infertility , andrology , follicular phase , oocyte , in vitro fertilisation , gene expression , female infertility , medicine , gene , biology , embryo , microbiology and biotechnology , genetics , pregnancy
Endometriosis is associated with infertility, even without an anatomical abnormality. Furthermore, the peritoneal (mild) phenotype of this disease is the most prevalent and linked to infertility. The present study aimed to investigate the p63 gene and protein expression in granulosa cells from pre-ovulatory follicles in patients with endometriosis and infertility submitted to in vitro fertilization.