Open AccessIs there a better evolutionary outcome in a 4-cell tetrahedron embryo?
Author(s) -
Marta Ribeiro Hentschke,
Ricardo Azambuja,
Victória Campos Dornelles,
Bibiana Cunegatto,
Cristina Hickman,
Rishabh Hariharan,
Isadora Badalotti Telöken,
Catarina Heckmann Petracco,
Fabiana Mariani Wingert,
Álvaro Petracco,
Mariângela Badalotti
Publication year - 2021
Publication title -
jbra
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 14
eISSN - 1518-0557
pISSN - 1517-5693
DOI - 10.5935/1518-0557.20210034
Subject(s) - blastocyst , embryo , tetrahedron , planar , embryonic stem cell , in vitro fertilisation , human fertilization , embryogenesis , biology , andrology , microbiology and biotechnology , chemistry , genetics , computer science , medicine , crystallography , computer graphics (images) , gene
With the growing understanding of in vitro fertilization and reproductive technology, the magnitude of studies related to embryonic evolution has also increased. The optimization of embryo selection is crucial to minimize the risk of multiple pregnancies and to guarantee successful implantation and pregnancy. On the second day of culture, the four-cell embryo can be shaped into different arrangements, such as tetrahedral and planar. Previous studies have shown that mammalian embryos have a tetrahedral shape and that any deviation from this ideal configuration can negatively affect blastocyst development. A few studies have also found that planar embryos would be linked to negative predictors of success for reaching the blastocyst stage and its good quality. Therefore, it seems that tetrahedral should be preferred over planar-shaped embryos for embryonic transfers, but there is still little understanding and evidence about this subject. Thus, the objective of the present paper was to review the available literature on study tendencies to compare tetrahedral and planar-shaped embryos considering their effect on implantation and pregnancy results.