CREM, PRM I and II gene expression in Wistar rats testes treated with antipsychotic drugs: Chlorpromazine, Rauwolfia vomitoria and co-administration of reserpine, zinc and ascorbic acid | Zendy

Adeleke Opeyemi | Zendy; Oyewopo Adeoye | Zendy; Akingbade Adebanji | Zendy; Olawumi Johnson | Zendy

Open Access

CREM, PRM I and II gene expression in Wistar rats testes treated with antipsychotic drugs: Chlorpromazine, Rauwolfia vomitoria and co-administration of reserpine, zinc and ascorbic acid

Author(s) -

Adeleke Opeyemi,

Oyewopo Adeoye,

Akingbade Adebanji,

Olawumi Johnson

Publication year - 2020

Publication title -

jbra

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.596

H-Index - 14

eISSN - 1518-0557

pISSN - 1517-5693

DOI - 10.5935/1518-0557.20200058

Subject(s) - reserpine , chlorpromazine , pharmacology , endocrinology , antipsychotic , medicine , reproductive toxicity , toxicity , testosterone (patch) , chemistry , schizophrenia (object oriented programming) , psychiatry

The literature has shown that synthetic antipsychotic drugs induce reproductive toxicity, while psychiatric patients treated with traditionally used antipsychotic herbs (Rauwolfia vomitoria) showed no traces of reproductive toxicity. Thus, this study aimed to investigate the expression of CREM, PRM I and II genes in the testes of Wistar rats treated with antipsychotic drugs: chlorpromazine, Rauwolfia vomitoria (RV) and co-administration of reserpine, zinc and ascorbate (RAZ).

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