Open AccessProtective effects of methanol extract of Plukenetia conophora seeds and 4H-Pyran-4-One 2,3-Dihydro-3,5-Dihydroxy-6-Methyl on the reproductive function of male Wistar rats treated with cadmium chloride
Author(s) -
Charles Oluwaseun Adetunji,
Olufadekemi Tolulope Kunle-Alabi,
Yinusa Raji
Publication year - 2018
Publication title -
jbra
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 14
eISSN - 1518-0557
pISSN - 1517-5693
DOI - 10.5935/1518-0557.20180048
Subject(s) - malondialdehyde , chemistry , cadmium chloride , saline , nitric oxide , sperm motility , sperm , cadmium , antioxidant , andrology , zoology , endocrinology , biochemistry , biology , medicine , organic chemistry
Male infertility caused by exposure to heavy metals is a current global issue. Exposure to cadmium chloride (CdCl 2 ) negatively affects the male reproductive system. Many infertile people, especially in developing countries, resort to folkloric treatment. Plukenetia conophora is used in Nigerian folk medicine to promote fertility. This study investigated the effects of Plukenetia conophora (PC) and 4H-Pyran-4-One 2,3-Dihydro-3,5-Dihydroxy-6-Methyl (DDMP) on Wistar rats with cadmium chloride-induced testicular damage.