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High percentages of embryos with 21, 18 or 13 trisomy are related to advanced paternal age in donor egg cycles
Author(s) -
Javier García-Ferreyra,
Roly Hilario,
J.I. Ramos Dueñas
Publication year - 2018
Publication title -
jbra
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.596
H-Index - 14
eISSN - 1518-0557
pISSN - 1517-5693
DOI - 10.5935/1518-0557.20180004
Subject(s) - aneuploidy , embryo , trisomy , andrology , biology , sperm , embryo quality , human fertilization , zygote , advanced maternal age , in vitro fertilisation , gynecology , embryogenesis , pregnancy , chromosome , genetics , medicine , fetus , gene
Advanced paternal age is related to poor sperm quality; however, little is known on its effect on aneuploidy embryo rates and, more importantly, on chromosomal abnormalities like trisomy 21, 18 and 13. The objective of this study was to evaluate the effect of advanced paternal age on the trisomy rates of the chromosomes 21, 18 or 13 in embryos obtained from donated oocytes.