Open AccessKounis syndrome. Apropos of a clinical case
Author(s) -
Pedro Duarte,
Joana Costa,
C Serena,
Carla Almeida,
Sandra Gouveia,
César Lourenço,
Humberto Costa,
Clara Paiva
Publication year - 2020
Publication title -
revista brasileira de terapia intensiva
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.431
H-Index - 19
eISSN - 1982-4335
pISSN - 0103-507X
DOI - 10.5935/0103-507x.20200021
Subject(s) - kounis syndrome , medicine , coronary arteries , anaphylaxis , cardiology , acute coronary syndrome , context (archaeology) , hypersensitivity reaction , anamnesis , allergy , artery , myocardial infarction , paleontology , immunology , biology
Kounis syndrome, while an acute coronary syndrome, occurs in the context of a hypersensitivity reaction, allergies, or anaphylaxis and is subdivided into three types: coronary spasm in normal arteries, instability of plaques in atherosclerotic coronary arteries, and thrombosis of coronary stents. Herein, the case of a 73-year-old patient who, after administration of amoxicillin/clavulanic acid, went into cardiorespiratory arrest with evidence of ST-T segment elevation on electrocardiogram is reported. Coronarography revealed no obstructive lesions, and spontaneous resolution of electrocardiographic abnormalities was observed. A review of anamnesis with the family revealed a previous allergy to penicillin. The tryptase dosage was strongly positive. Kounis syndrome type 2 was diagnosed, and the clinical outcome was good.