Open AccessWith rising global energy demands and the perception of an imminent lack of petroleum, a main source of energy, comes a big rush for renewable and sustainable energetic sources. In Brazil, a reasonable fraction of energy comes from biomass, a renewable source with increasing energetic potential, not only for the direct production of energy in combustion but also as feedstock in the chemical industry. In this context, Bio-Methanol arises as one of the possible substitutes for petroleum fuels, since it can come from renewable sources, has excellent fuel properties and low CO2 emissions. Bio-Methanol produced from biomass via gasification is well known, and its advantages are increasing, with new studies and technologies appearing around the process. This literature review summarizes recent technology for bio-methanol production and the economics of large-scale applications, presenting the advantages of the process along with the future prospects of bio-methanol in Brazil.