Open AccessAcute angle closure triggered by oral benzodiazepines
Author(s) -
Alexis Galeno Matos,
Pedro Duarte Barreto Castillo,
João Augusto Lima Bisneto,
Jayter Silva Paula
Publication year - 2021
Publication title -
arquivos brasileiros de oftalmologia
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.603
H-Index - 29
eISSN - 1678-2925
pISSN - 0004-2749
DOI - 10.5935/0004-2749.20210017
Subject(s) - clonazepam , medicine , alprazolam , blinding , adverse effect , glaucoma , anesthesia , ophthalmology , clinical trial , anxiety , psychiatry
Benzodiazepines are psychoactive drugs that are prescribed worldwide with limited information on their ocular side effects. Acute angle closure glaucoma is an adverse event with a high risk of blinding, especially in the elderly. We report two patients under 45 years old who presented with bilateral acute angle closure secondary to use of two long half-life benzodiazepines (clonazepam and alprazolam). In addition to suspending the use of these medications and administering ocular hypotensive drugs, both patients were successfully treated with bilateral peripheral laser iridotomy. To the best of our knowledge, this is the first report of bilateral acute angle closure secondary to the use of clonazepam and alprazolam.