Open AccessLiver regeneration in nonalcoholic fatty liver disease
Author(s) -
Aldo Lagomarsino
Publication year - 2012
Publication title -
medwave
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.178
H-Index - 7
ISSN - 0717-6384
DOI - 10.5867/medwave.2012.11.5559
Subject(s) - nonalcoholic fatty liver disease , politics , medicine , regeneration (biology) , fatty liver , peer review , political science , clinical research , nonalcoholic steatohepatitis , disease , gerontology , library science , law , biology , computer science , microbiology and biotechnology
Steatosis is the accumulation of fat in hepatocytes, which may be the result of liver regeneration or pathological processes such as alcoholic and nonalcoholic fatty liver disease. Despite its importance, in both cases the exact mechanism that prevails in fatty liver regeneration is poorly understood. Previous studies have shown that patients with fatty liver express dispar regeneration, possibly due to the accumulation of reactive oxygen species generated by inflammatory processes caused by activation of Kupffer cells. In this article we review several factors that affect liver regeneration, trying to understand the underlying mechanism of dispar regeneration in fatty liver as a consequence of nonalcoholic fatty liver disease