Open AccessLate Acetaminophen Therapy for Patent Ductus Arteriosus in the Preterm Neonate
Author(s) -
Robert King,
Michael Colon,
Laura Stanfel,
Kate A. Tauber
Publication year - 2020
Publication title -
the journal of pediatric pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 15
eISSN - 2331-348X
pISSN - 1551-6776
DOI - 10.5863/1551-6776-25.6.507
Subject(s) - medicine , ductus arteriosus , acetaminophen , ibuprofen , anesthesia , ligation , pharmacology
In preterm infants, the standard pharmacologic treatment for a hemodynamically significant patent ductus arteriosus (hsPDA) is either ibuprofen or indomethacin. However, these medications may be less effective after 2 weeks of age. We investigated the use of acetaminophen in hsPDA closure beyond 2 weeks of age.