Open AccessInjectable Dexamethasone Sodium Phosphate Administered Orally? A Pharmacokinetic Analysis of a Common Emergency Department Practice
Author(s) -
Alexander H. Toledo,
Christopher S. Amato,
Nigel J. Clarke,
Richard E. Reitz,
D. Salo
Publication year - 2015
Publication title -
the journal of pediatric pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 15
eISSN - 2331-348X
pISSN - 1551-6776
DOI - 10.5863/1551-6776-20.2.105
Subject(s) - cmax , medicine , dexamethasone , pharmacokinetics , bioavailability , confidence interval , area under the curve , pharmacology
The injectable formulation of dexamethasone has been administered orally, for the treatment of pediatric asthma and croup. The practice is followed in emergency departments around the country, but pharmacokinetic data supporting this practice are lacking.