Open AccessEvaluation of Enoxaparin Dosing and Monitoring in Pediatric Patients at Children's Teaching Hospital
Author(s) -
Elizabeth W. McCormick,
Kristine A. Parbuoni,
Donna Huynh,
Jill A. Morgan
Publication year - 2015
Publication title -
the journal of pediatric pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 15
eISSN - 2331-348X
pISSN - 1551-6776
DOI - 10.5863/1551-6776-20.1.33
Subject(s) - medicine , dosing , therapeutic effect , mann–whitney u test , pediatrics
The primary objective of this study was to evaluate whether empirical enoxaparin doses according to Chest guidelines resulted in therapeutic antifactor Xa concentrations in pediatric patients. Secondary objectives were to determine the median enoxaparin dose that resulted in therapeutic anticoagulation, the median time to therapeutic concentrations, and the percentage of patients who experienced major bleeding.