
Clevidipine Controls Intraoperative Blood Pressure In an Adolescent with Renal Failure
Author(s) -
Joseph D. Tobias,
Joy Allee,
Venkataraman Ramachandran,
Ted Groshong
Publication year - 2009
Publication title -
the journal of pediatric pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 15
eISSN - 2331-348X
pISSN - 1551-6776
DOI - 10.5863/1551-6776-14.3.144
Subject(s) - medicine , perioperative , blood pressure , anesthesia , peritoneal dialysis , dialysis , volume overload , catheter , anesthetic , heart failure , intensive care medicine , surgery
In pediatric-aged patients, various factors may result in perioperative hypertension including renal failure or insufficiency, volume overload, or other factors that activate the sympathetic nervous system including pain and agitation. Perioperative blood pressure control may be even more difficult to achieve and maintain in patients with pre-existing hypertension. We present a 16-year-old adolescent with renal failure and hypertension who presented for anesthetic care during placement of a peritoneal dialysis catheter. Perioperative blood pressure control was achieved with the administration of clevidipine, an ultra-short acting calcium channel antagonist of the dihydropyridine class. Its role in the perioperative control of blood pressure is discussed.