Open AccessMorphologic Changes in the Thymus Following Chemotherapy for Anterior Mediastinal Germ Cell Tumors: A Study of 91 Cases Emphasizing Pseudoneoplastic Features
Author(s) -
Tieying Hou,
David Levy,
Thomas M. Ulbright
Publication year - 2022
Publication title -
archives of pathology and laboratory medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.79
H-Index - 117
eISSN - 1543-2165
pISSN - 0003-9985
DOI - 10.5858/arpa.2021-0631-oa
Subject(s) - yolk sac , pathology , atypia , thymic carcinoma , germ cell tumors , biology , germ cell , chemotherapy , teratoma , metaplasia , medicine , thymoma , embryo , biochemistry , gene , microbiology and biotechnology
The interpretation of postchemotherapy resections of anterior mediastinal germ cell tumors plays a critical role in determining future patient management and prognosis. Treatment-related changes in the thymus may mimic residual teratoma or microcystic-pattern yolk sac tumor. There is limited extant information concerning therapy-related pseudoneoplastic thymic alterations.