Open AccessProtective effect of exogenous IGF-I on the intestinal mucosal barrier in rats with severe acute pancreatitis
Author(s) -
Yingzhen Wang,
Shiwen Wang,
Youcheng Zhang,
Zhi-Jiang Sun
Publication year - 2012
Publication title -
world journal of emergency medicine
Language(s) - English
Resource type - Journals
ISSN - 1920-8642
DOI - 10.5847/wjem.j.issn.1920-8642.2012.03.010
Subject(s) - medicine , acute pancreatitis , pancreatitis , saline , small intestine , endocrinology , tunel assay , amylase , apoptosis , group b , gastroenterology , andrology , immunohistochemistry , biology , enzyme , biochemistry
Severe acute pancreatitis (SAP) can result in intestinal mucosal barrier (IMB) dysfunction. This study was undertaken to demonstrate the effect of IGF-I on the intestinal mucosal barrier in rats with SAP and its possible mechanisms.