Open AccessEffects of hyperbaric oxygen on intestinal mucosa apoptosis caused by ischemia-reperfusion injury in rats
Author(s) -
Shi-hui Zhou,
Yanan Sun,
Gang Wang
Publication year - 2012
Publication title -
world journal of emergency medicine
Language(s) - English
Resource type - Journals
ISSN - 1920-8642
DOI - 10.5847/wjem.j.issn.1920-8642.2012.02.010
Subject(s) - medicine , ischemia , reperfusion injury , superior mesenteric artery , intestinal ischemia , ileum , apoptosis , hyperbaric oxygen , small intestine , anesthesia , intestinal mucosa , gastroenterology , biochemistry , chemistry
Hyperbaric oxygen (HBO) is an effective adjuvant therapy for ischemia- reperfusion (I/R) injury of the brain, small intestine and testis in addition to crushing injury. Studies have shown that HBO increases the activity of villi of the ileum 30 minutes after I/R injury. The present study aimed to observe the effect of HBO on apoptosis of epithelial cells in the small intestine during different periods of I/R and to elucidate the potential mechanisms.