Open AccessCardiac surgery-associated acute kidney injury: pathophysiology and diagnostic modalities and management
Author(s) -
Gontse Leballo,
Palesa Motshabi Chakane
Publication year - 2020
Publication title -
cardiovascular journal of south africa/cardiovascular journal of southern africa
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.378
H-Index - 35
eISSN - 1680-0745
pISSN - 1015-9657
DOI - 10.5830/cvja-2019-069
Subject(s) - medicine , acute kidney injury , pathophysiology , renal replacement therapy , intensive care medicine , kidney disease , cardiac surgery , complication , disease , modalities , kidney , social science , sociology
Acute kidney injury is a disease spectrum that can present with from mild renal dysfunction to complete renal failure that would require renal replacement therapy. Cardiac surgery-associated acute kidney injury is a complication that carries a grave disease burden. Risk factors are identified as being either modifiable or non-modifiable. This literature review aims to define the pathophysiology of cardiac surgery-associated acute kidney injury, the current definition and classification of acute kidney injury and the available diagnostic modalities, especially the use of biomarkers.