Open AccessCoexistence of Crohn’s Disease and Hodgkin’s Lymphoma in a Young Man with Rectorrhagia
Author(s) -
Ahmad Hormati,
Mohammad Reza Ghadir,
Seyed Saeed Sarkeshikian,
Abolfazl Iranikhah,
Mahdieh Ghoddoosi
Publication year - 2017
Publication title -
murāqibat-i bīmārī/hā-yi muzmin-i jundī/shāpūr
Language(s) - English
Resource type - Journals
eISSN - 2322-4207
pISSN - 2322-3758
DOI - 10.5812/jjcdc.42794
Subject(s) - medicine , disease , lymphoma , crohn's disease , azathioprine , colorectal cancer , gastroenterology , cancer , abdominal pain , incidence (geometry) , inflammatory bowel disease , diarrhea , physics , optics
Crohn’s disease (CD) is an inflammatory disease with an increasing incidence and can involve any part of the gastrointestinal tract. Most cases are seen in young adults presenting with abdominal pain and diarrhea. This condition may lead to complications such as stricture and fistula. Besides, there is an increased risk of colorectal cancer and some extraintestinal cancers in these patients, due to chronic inflammation. One of the therapeutic options for Crohn’s patients is the use of immunomodulators. Such agents can induce remission and limit the usage of steroids. According to some literature, this treatment can increase the risk of colorectal cancer as well as extraintestinal cancers, of which skin cancers and lymphoma are the most prevalent. Lymphoma can be a result of chronic inflammation or use of immunomodulators such as azathioprine and 6-mercaptopurine (6-MP).Case PresentationIn this literature, we describe a young man with rectorrhagia who is diagnosed with Crohn’s disease and a coexistence of lymphoma at the time of diagnosis, without a history of immunomodulator therapy.ConclusionsWith attention to the increased risk of colorectal and extraintestinal cancer in Crohn’s patients, assessment for early diagnosis should be considere