Open AccessThe Role of Ketone Bodies in Improving Neurological Function and Efficiency
Author(s) -
Deepanshu Naithani,
Santosh Kumar Karn
Publication year - 2020
Publication title -
health scope
Language(s) - English
Resource type - Journals
eISSN - 2251-9513
pISSN - 2251-8959
DOI - 10.5812/jhealthscope.86578
Subject(s) - ketone bodies , neurocognitive , glycolysis , citric acid cycle , ketone , bioenergetics , biochemistry , biomolecule , energy metabolism , lipid metabolism , chemistry , neuroscience , biology , metabolism , mitochondrion , endocrinology , cognition , organic chemistry
: Neurological coordination is essential for performing biological and mechanical activities achieved by the cooperation of biomolecules such as carbohydrates, lipids, and proteins. It plays an important role in energy production, which can be fascinatingly improved by ketone bodies. Ketone bodies are small, water-soluble lipid molecules by shifting the glycolytic phase KBs directly enters into the tricarboxylic acid cycle for ATP synthesis. It leads to the production of much more energy levels than a single molecule of glucose. Therefore, it could have a profound effect on neuro-metabolism as well as bioenergetics of ATP production. These neuro-enhancement properties are useful for epilepsy, Alzheimer's, and several neurocognitive disorders treatment. Interestingly, the cancer cells cannot use it for efficiently energy production results in decreasing cancer cells viability. This review summarized ketone bodies generation, related imperative effects on normal cells, and more importantly its application in various neurological disorders treatment by rising neuronal functions.