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Elimination of Helicobacter pylori Infection in Patients with Gastrointestinal Problems After Administration of Four-Drug Regimen: A Brief Report
Author(s) -
Mohammad Hosseini Azar,
Mohammad Jafari Heidarloo,
Hamze Majidi,
Sahar Paryab,
Omid Garkaz,
Hamid Reza Mehryar
Publication year - 2021
Publication title -
journal of archives in military medicine
Language(s) - English
Resource type - Journals
eISSN - 2345-5063
pISSN - 2345-5071
DOI - 10.5812/jamm.117373
Subject(s) - indigestion , medicine , regimen , helicobacter pylori , incidence (geometry) , checklist , drug , helicobacter pylori infection , helicobacter , gastroenterology , pharmacology , physics , optics , psychology , cognitive psychology
Background: There are a variety of treatment regimens containing several antimicrobial compounds to treat Helicobacter pylori infection. Objectives: The aim of this study was to eradicate H. pylori infection in patients with gastrointestinal problems after the administration of a four-drug regimen. Methods: This study was performed among 100 patients with gastrointestinal problems visiting Imam Khomeini Hospital in Urmia, Iran. The data were collected using a checklist that included patient information and analyzed by chi-square and t-test. Results: Out of the 100 patients visiting the clinic, 60 (60%) were male, and the rest were women. Also, 67% of the patients had pain type dyspepsia, and 33% of them postprandial distress type. In pathologic study, 38% of the patients had H. pylori infection, with a significantly higher incidence in patients with pain type dyspepsia. Conclusions: The results showed a relationship between the type of indigestion and the improvement of symptoms after receiving a four-drug regimen, indicating the need for proper planning to diagnose and treat the type of indigestion.

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