Open AccessA Complicated Case of Stroke, Epilepsy, and Mood Disorder: Hyperhomocysteinemia or Medication Cascade
Author(s) -
Fatemeh Mohammadian,
Homayoun Amini,
Niayesh Mohebbi,
Amirhossein Jafari-Mehdiabad
Publication year - 2021
Publication title -
iranian journal of psychiatry and behavioral sciences/iranian journal of psychiatry and behavioral sciences.
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.28
H-Index - 17
eISSN - 1735-9287
pISSN - 1735-8639
DOI - 10.5812/ijpbs.107679
Subject(s) - hyperhomocysteinemia , medicine , stroke (engine) , epilepsy , carbamazepine , mood , mood disorders , pediatrics , disease , psychiatry , homocysteine , mechanical engineering , anxiety , engineering
Hyperhomocysteinemia is a risk factor for atherosclerosis and vascular disease, which is correlated with cerebral problems and various neurological disorders. Case presentation: We report a 20-year-old lady with a history of hyperhomocysteinemia affected with stroke, seizure, and mood disorder. By initiating medication for these illnesses, different complications appeared. During the hospital stay, drugs for treating a disease deteriorated the other. We encountered a complex patient and numerous ambiguities in her management. Conclusions: For patients with elevated serum homocysteine and psychiatry disorders, it is important to consider MTHFR gene mutation. A challenge in these patients is to select the medication that does not deteriorate hyperhomocysteinemia. In this complex case, we used carbamazepine that was accompanied by clinical improvement.