Open AccessPost-Exchange Transfusion Sodium Change Within a Laboratory Reference Range of Serum in Hospitalized Severe Neonatal Jaundice Cases
Author(s) -
Amir-Kamal Hardani,
Masood Zadkarami,
Asaad Sharhani,
Shirin Rashidi Mehrabadi
Publication year - 2021
Publication title -
iranian journal of pediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.168
H-Index - 25
eISSN - 2008-2150
pISSN - 2008-2142
DOI - 10.5812/ijp.104582
Subject(s) - medicine , jaundice , exchange transfusion , abo incompatibility , pediatrics , kernicterus , birth weight , breastfeeding , abo blood group system , gastroenterology , pregnancy , genetics , biology
Background: Blood exchange transfusion (ECT) therapy is an essential part of the modern health care for high-risk icteric neonates. Objectives: Therefore, this study sought to examine the effectiveness of monitoring sodium disorders and the required interventions indicating the overall state of health of hospitalized jaundiced neonates. Methods: This prospective analytic study was performed on 49 neonates diagnosed with severe jaundice undergoing screened exchange blood transfusion from November 2018 to May 2019. Serum sodium ion concentrations testing was performed before the exchange, then 1 - 3 hours later, and again 24 hours after receiving ECT, using a sensitive ELISA kit in a laboratory. Using the newest version of SPSS 24 software program, the association between different numerical variables was calculated by a repeated-measure ANOVA test. P 0.05). Conclusions: Given these facts, it was concluded that neonatal jaundice was significantly associated with post-exchange serum sodium changes within the laboratory reference range of serum.