Open AccessLow-Dose Ketamine Infusion Versus Morphine Infusion During Abdominoplasty to Change the Postoperative Pain Profile
Author(s) -
Hassan Ali,
Amr Ismail,
Amr Samir Wahdan
Publication year - 2020
Publication title -
anesthesiology and pain medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.438
H-Index - 26
eISSN - 2228-7531
pISSN - 2228-7523
DOI - 10.5812/aapm.108469
Subject(s) - medicine , ketamine , abdominoplasty , anesthesia , morphine , fentanyl , sedation , visual analogue scale , analgesic , opioid , side effect (computer science) , randomized controlled trial , surgery , plastic surgery , receptor , computer science , programming language
Background: With the increased number of abdominoplasty all over the world, and the need to manage postoperative pain, it is a must to find proper and effective drugs to decrease opioid consumption in the postoperative period. Objectives: In this double-blind randomized controlled clinical trial, we assumed that low-dose ketamine infusion will reduce the postoperative pain profile than the conventional method of morphine. Methods: The scheduled patients for abdominoplasty under general anesthesia were recruited in two groups: group (K) with low-dose ketamine infusion intra-operatively (80 patients) and group (M) with morphine infusion intra-operatively (80 patients). Both groups were monitored intraoperatively and postoperatively for rescue doses of fentanyl, visual analogue scale (VAS), and side effects. Results: There were no statistical differences between both groups regarding the fentanyl rescue doses intra- and postoperative with no remarkable side effects. Conclusions: Low-dose ketamine has a useful analgesic effect in abdominoplasty similar to morphine without remarkable side effects, such as sedation or hallucinations.