Open AccessThis study addresses some fundamental problems of tectonics and geodynamics of the Central Asian folded belt, the largest tectonic structure in Eurasia. The article presents results of long-term researches conducted by scientists and geologists specialized in various disciplines which contribute to the knowledge of the origin and breakup of Rodinia and formation of the Paleo-Asian Ocean. It considers problems of development of the Central Asian folded belt that was formed in the area of the Paleo-Asian Ocean and describes its subduction magmatism and marginal-marine sedimentation, formation of island arcs, processes of exhumation of the oceanic crust and formation of high-pressure blueschist and eclogite-blueschist complexes. Outstanding fundamental issues of the geodynamic evolution of the Central Asian folded belt are noted.