Open AccessEXPOSIÇÃO PÓS-NATAL ÀPOLUENTES DO AR (MP≤2,5) COMO FATOR DE RISCO PARA O DESENVOLVIMENTO DE COMPORTAMENTOS DE DEPRESSÃO E ANSIEDADE: UM ESTUDO EXPERIMENTAL
Author(s) -
Carla de Oliveira Carletti,
Rodrigo Correia Santos,
Luis Fernando Sierra de Araújo,
Murilo Américo de Paiva Santos,
Mariana Matera Veras,
Regina H. Silva,
Maria Joséda Silva Fernandes
Publication year - 2019
Publication title -
colloquium vitae
Language(s) - English
Resource type - Journals
ISSN - 1984-6436
DOI - 10.5747/cv.2019.v11.n3.v267
Subject(s) - open field , statistical significance , psychology , anxiety , physiology , medicine , psychiatry
The purpose of thestudy was to evaluate the behavioral changes of male and female adultrats exposed to fine and ultrafine particulate matter (PM≤2,5) suspended in air pollution during development. Wistar rats aged 7 postnataldayswere exposed to the chamber of an atmospheric particle concentrator. Open field tests and sucrose preference tests were performed to assess the presence of anxiety and depression behaviors. Male rats from the pollution group showed reduced locomotor activity and length of stay in the open field center when compared to the control group. The sucrose preference test showed statistical significance between the pollution and control groups(male+female), and among the males of the pollution and control group.The study concluded thatexposure to PM≤2.5 causes behavioral changes characteristic of depression and anxietyin adult male rats exposed during the developmental period.