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Carbapenemase‐producing Klebsiella pneumoniae: a major clinical challenge
Author(s) -
Mandrawa Christine L,
Cronin Katie,
Buising Kirsty L,
Poy Lorenzo Yves S,
Waters Mary J,
Jeremiah Cameron J
Publication year - 2016
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/mja15.00885
Subject(s) - klebsiella pneumoniae , microbiology and biotechnology , klebsiella , medicine , intensive care medicine , biology , escherichia coli , biochemistry , gene
A 59-year-old man from rural Victoria, with no hospital contact for 15 years or recent history of international travel, presented to his local hospital with severe acute pancreatitis secondary to gallstones. He was transferred to a metropolitan hospital for further management, including intermittent admissions to the intensive care unit (ICU) for haemodynamic support. On Day 4 of admission, empirical antibiotics were prescribed for severe pancreatitis and concurrent nosocomial pneumonia, according to hospital guidelines and advice from the infectious diseases team; initially ceftriaxone, later changed to piperacillinetazobactam and then meropenem, due to clinical deterioration. Diagnostic microbiology did not reveal any significant pathogens.