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Summary statement: new guidelines for the management of paracetamol poisoning in Australia and New Zealand
Author(s) -
Chiew Angela L,
Fountain John S,
Graudins Andis,
Isbister Geoffrey K,
Reith David,
Buckley Nicholas A
Publication year - 2015
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/mja15.00614
Subject(s) - statement (logic) , operations research , medicine , engineering , political science , law
Alarge proportion of accidental paediatric exposures and deliberate self-poisoning incidents involve paracetamol; it is the leading pharmaceutical agent responsible for calls to Poisons Information Centres in Australia and New Zealand. Management of paracetamol poisoning has altered since the previous guidelines were published in 2008, so that they do not reflect current practice by clinical toxicologists. The key changes from the previous guidelines concern the indications for administration of activated charcoal; the management of patients taking large or massive overdoses; modified-release and supratherapeutic ingestions; and paediatric liquid paracetamol ingestion.