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Local acquisition and nosocomial transmission of Klebsiella pneumoniae harbouring the blaNDM‐1 gene in Australia
Author(s) -
Tai Alex Y C,
Stuart Rhonda L,
Sidjabat Hannah E,
Lemoh Christopher N,
Rogers Benjamin A,
Graham Maryza,
Paterson David L,
Korman Tony M
Publication year - 2015
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/mja14.01637
Subject(s) - klebsiella pneumoniae , microbiology and biotechnology , biology , transmission (telecommunications) , gene , genetics , escherichia coli , computer science , telecommunications
Patient A, a 68-year-old Australian-born woman living with her husband and son, had never travelled overseas and had no known contact with overseas visitors. Her past history included chronic bilateral lymphoedema with recurrent lower limb cellulitis, requiring multiple previous hospital admissions and home nursing care. She presented with septic shock and right leg erythema surrounding a 10 10 cm ulcer near the right lateral malleolus. Magnetic resonance imaging showed bony oedema and enhancement in the lateral malleolus, suggestive of osteomyelitis. Pseudomonas aeruginosa was isolated from blood cultures. A tissue biopsy from the overlying ulcer cultured P. aeruginosa, non-multiresistant methicillinresistant Staphylococcus aureus (NORSA), and carbapenemresistant Klebsiella pneumoniae, resistant to all first-line antimicrobials tested and susceptible to only colistin and fosfomycin.