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Treatment and prevention of Mycobacterium ulcerans infection (Buruli ulcer) in Australia: guideline update
Author(s) -
O'Brien Daniel P,
Jenkin Grant,
Buntine John,
Steffen Christina M,
McDonald Anthony,
Horne Simon,
Friedman N Deborah,
Athan Eugene,
Hughes Andrew,
Callan Peter P,
Johnson Paul D R
Publication year - 2014
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/mja13.11331
Subject(s) - buruli ulcer , mycobacterium ulcerans , guideline , medicine , antibiotics , intensive care medicine , antibiotic therapy , disease , dermatology , pathology , biology , microbiology and biotechnology
Summary Guidelines reflecting contemporary clinical practice in the management of Buruli ulcer ( Mycobacterium ulcerans infection) in Australia were published in 2007. Management has continued to evolve, as new evidence has become available from randomised trials, case series and increasing clinical experience with oral antibiotic therapy. Therefore, guidelines on the diagnosis, treatment and prevention of Buruli ulcer in Australia have been updated. They include guidance on the new role of antibiotics as first‐line therapy; the shortened duration of antibiotic treatment and the use of all‐oral antibiotic regimens; the continued importance, timing and role of surgery; the recognition and management of paradoxical reactions during antibiotic treatment; and updates on the prevention of disease.