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Determining research priorities for clinician‐initiated trials in infectious diseases
Author(s) -
Paterson David L
Publication year - 2013
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/mja12.11703
Subject(s) - medicine , intensive care medicine , randomized controlled trial , septic arthritis , infectious disease (medical specialty) , osteomyelitis , alternative medicine , family medicine , immunology , disease , arthritis , pathology
Abstract Objectives: To determine research priorities of infectious diseases physicians for clinician‐initiated randomised controlled trials (RCTs). Design, setting and participants: Online survey of infectious diseases physicians in Australia and New Zealand. Main outcome measures: Research priorities for, and perceived barriers to, clinician‐initiated RCTs. Results: 122/550 infectious diseases physicians (22%) responded to the survey. The five highest ranked proposals for clinician‐initiated RCTs were in the areas of prosthetic joint infections, septic arthritis and osteomyelitis of native joints, Staphylococcus aureus bloodstream infections, diabetic foot infections and the treatment of serious multiresistant, gram‐negative bacterial infections. Lack of funding was the most important perceived barrier to participation in clinician‐initiated RCTs. Conclusions: The research focus of infectious diseases physicians — optimal treatment of commonly encountered serious infections — highlights a lack of well conducted RCTs in this area.