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A case of discordant HbA1c: a method‐dependent error
Author(s) -
Dimeski Goce,
Pretorius Carel J,
Russell Anthony W,
Miller Stephen P,
Bird Robert J,
Ungerer Jacobus P J
Publication year - 2009
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.2009.tb02821.x
Subject(s) - general hospital , medical laboratory , medicine , library science , pathology , family medicine , computer science
Although glycated haemoglobin (HbA(1c)) has become the key biochemical marker of long-term glycaemic control, analytical method-dependent differences in results can occur when haemoglobin variants are present or HbA(1c) is reduced by decreased red cell survival. When the measured HbA(1c) level is discordant with the patient's blood glucose measurements and clinical status, fructosamine is an alternative biochemical marker that can provide a more accurate estimate of the glycaemic control and enable clinicians to appropriately manage patients.