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Oocyte freezing: timely reproductive insurance?
Author(s) -
Molloy David,
Hall Barbara A,
Ilbery Marianne,
Irving Jacqui,
Harrison Keith L
Publication year - 2009
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.2009.tb02385.x
Subject(s) - oocyte , andrology , medicine , biology , genetics , embryo
Cryopreservation of unfertilised oocytes for later use in initiating pregnancy is now a viable technology, with acceptable pregnancy rates (over 20% per thaw cycle). Oocyte cryopreservation used as a form of insurance against “social” (age‐related) infertility can improve the lifetime chance of pregnancy in women who defer pregnancy into their late 30s or early 40s. We report two pregnancies using oocytes that were frozen for social rather than medical reasons, as part of a larger series of nine pregnancies using cryopreserved oocytes. Use of oocytes harvested and frozen from women aged under 35 years may more than double the chance of pregnancy for a 41‐year‐old woman. The disadvantages of oocyte freezing for social infertility reasons include cost, the usual risks associated with in‐vitro fertilisation, and the lack of a guarantee of eventual pregnancy.