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Ocular pigmentation associated with clozapine
Author(s) -
Borovik Armand M,
Bosch Martina M,
Watson Stephanie L
Publication year - 2009
Publication title -
medical journal of australia
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.2009.tb02353.x
Subject(s) - watson , ophthalmology , officer , medicine , art , optometry , history , archaeology , computer science , artificial intelligence
A 55-year-old woman who was treated with long-term, high-dose clozapine for schizophrenia presented with bilateral decreased visual acuity. She had pigmentary changes affecting the cornea and the retina, as well as stellate cataract. Chlorpromazine use is known to produce similar changes, but this is the first report to our knowledge of pigmentation associated with clozapine use.