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Is the pharmacology of corticosteroids in the lung modified by age?
Author(s) -
Seale J Paul
Publication year - 2005
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.2005.tb06920.x
Subject(s) - medicine , pharmacology , lung
What we need to knowIs the lung in older patients with asthma less responsive to inhaled and systemic corticosteroids? (While anecdotal observations suggest this may be the case, no well conducted studies document the phenomenon.)What we need to doCarefully plan a clinical study to compare corticosteroid responsiveness between older people with asthma and their younger counterparts. Select sensitive and clinically relevant outcome variables for this study.