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Multiple analyses in clinical trials: sound science or data dredging?
Author(s) -
Lord Sarah J,
Gebski Val J,
Keech Anthony C
Publication year - 2004
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.2004.tb06376.x
Subject(s) - research centre , library science , clinical trial , medicine , computer science , pathology
ber 8 • 18 October 2004 452 MJA • Volume 181 Num NHMRC Clinical Trials Centre, University of Sydney, Sydney, NSW. Sarah J Lord, MB BS, MScEpid, Research Fellow; Val J Gebski, BA, MStat, Associate Professor and Principal Research Fellow; Anthony C Keech, MScEpid, FRACP, Deputy Director. Reprints will not be available from the authors. Correspondence: Dr Sarah J Lord, NHMRC Clinical Trials Centre, University of Sydney, Locked Bag 77, Camperdown, NSW 1450. enquiry@ctc.usyd.edu.au The Medical Journal of Australia ISSN: 0025729X 18 October 2004 181 8 452-454 ©The Medical Journal of Australia 2004 www.mja.com.au EBM: Trials on Trial that account for prognostic factors (adjusted analyse trial data to answer secondary research questions (s in Box 1). The use of trial data for population subg has been discussed earlier in this series.