Premium
Which substitution pharmacotherapy is most effective in treating opioid dependence?
Author(s) -
Gowing Linda R,
Ali Robert L,
White Jason M
Publication year - 2002
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.2002.tb04523.x
Subject(s) - addiction , medicine , library science , psychology , psychiatry , computer science
Interventions: (i) Levo acetyl methadol (LAAM) at 75–115 mg, (ii) buprenorphine at 16–32 mg, (iii) methadone at 60–100 mg (“high dose”), or (iv) methadone at 20 mg (“low dose”). LAAM and buprenorphine were given three times a week, methadone daily. LAAM and methadone were given orally, buprenorphine sublingually. Participants attended the clinic daily for two weeks of dose induction, then thrice weekly with take-home doses. The scheduled duration of the trial was 17 weeks.