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An analgesic role for cannabinoids
Author(s) -
Vaughan Christopher W,
Christle Macdonald J
Publication year - 2000
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.2000.tb125638.x
Subject(s) - analgesic , synthetic cannabinoids , cannabinoid receptor , cannabinoid , cannabis , medicine , chronic pain , cannabinoid receptor agonists , endocannabinoid system , pharmacology , clinical trial , human studies , neuroscience , receptor , psychiatry , biology , agonist
Cannabinoids have significant analgesic properties in animal models, particularly for chronic pain states, but there are few human studies. An endogenous cannabinoid system, with specific receptors and transmitters, has recently been discovered. This discovery has led pharmacologists to explore the potential of synthetic cannabinoids to selectively target chronic pain disorders without producing the side effects associated with cannabis. We/I‐controlled clinical trials on cannabinoids, and cannabinoid delivery systems, are now required.