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Incidence of bloodborne virus infection and risk behaviours in a cohort of injecting drug users in Victoria, 1990‐1995
Author(s) -
Crofts Nick,
Aitken Campbell K
Publication year - 1997
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1997.tb138757.x
Subject(s) - medicine , incidence (geometry) , cohort , seroconversion , transmission (telecommunications) , cohort study , prospective cohort study , hepatitis c , demography , human immunodeficiency virus (hiv) , environmental health , virology , physics , electrical engineering , sociology , optics , engineering
Objective To assess changes in risk behaviours for transmission of bloodborne viruses and incidences and prevalences of these viruses in a field‐recruited cohort of injecting drug users. Design Prospective longitudinal cohort study. Setting Metropolitan and rural Victoria, June 1990 to December 1995. Subjects 626 current injecting drug users (i.e., who had injected drugs within the previous 12 months). Main outcome measures Seroconversion to HIV and hepatitis B and C viruses (HBV and HCV); risk behaviours for infection. Results HIV incidence was very low (0.2 per 100 person‐years). HCV incidence was high (10.7 per 100 person‐years), but fell throughout the study, although the downward trend did not reach statistical significance. HBV incidence was moderate (1.8 per 100 person‐years) and did not fall. Prevalence of risk behaviours, notably sharing needles and syringes, decreased significantly. Conclusions Significant change has occurred in the risk behaviours of the cohort, confirming results of cross‐sectional studies of injecting drug use. This change may be responsible for the apparent decline in HIV and HCV incidence. Further studies are needed to monitor the incidence of bloodborne viruses in injecting drug users. Efforts to decrease risk of transmission should continue.