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The Chocuhaler: sweet deliverance in asthma management
Author(s) -
Hayden Mark J,
Wildhaber Johannes H,
Eber Ernst,
Devadason Sunalene G
Publication year - 1995
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1995.tb124760.x
Subject(s) - bronchodilator , salbutamol , asthma , medicine , inhalation , anesthesia
Objective To determine the characteristics of a new cocoa‐based edible spacer device for the delivery of aerosol bronchodilator. Design In‐vitro comparison of two spacer devices (standard and edible) and determination of bronchodilator response using the edible spacer. Setting A university children's hospital in Western Australia. Subjects Two volunteers with moderate asthma. Results Compared with a standard spacer, the edible spacer delivered significantly more bronchodilator in droplets of a size likely to enter the respiratory tract. A significant bronchodilator response occurred in two out of two subjects when salbutamol was inhaled orally via the chocolate spacer. No significant bronchodilator response occurred in either subject when the spacer was eaten at the end of the study. Conclusion The chocolate spacer used in this study is a suitable device to deliver salbutamol by inhalation. However, there may be potential drawbacks of weight gain in some patients and meltdown in hot climates.