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Planar cardiac F‐18 fluorodeoxyglucose imaging with a conventional gamma camera
Author(s) -
Kalff Victor,
Van Every Bruce,
Rowe Joy L,
Barton Howard J,
Kelly Michael J,
Lambrecht Richard M,
Leaney Peter,
Jamieson Christopher R
Publication year - 1994
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1994.tb127521.x
Subject(s) - gamma camera , medicine , fluorodeoxyglucose , nuclear medicine , myocardial perfusion imaging , positron emission tomography , cardiac imaging , thallium , cardiac pet , perfusion , radiology , materials science , metallurgy
Objective To examine the potential of an adapted gamma camera to image cardiac uptake of the positron emitting glucose analogue fluorine‐18 fluorodeoxyglucose (FDG). Design Postprandial studies were performed in 19 patients (mean age, 56 ± 9 years) with coronary disease and resting cardiac dysfunction who had undergone a routine clinical 7 min I view planar thallium‐201 (Tl‐201) stress reinjection or rest redistribution study. A glucose/insulin protocol was used and, an hour after FDG injection, 15‐minute static planar myocardial images were acquired in the four views used for Tl‐201 scanning. Results The diagnostic quality of FDG images was at least as good as that of their Tl‐201 counterparts, with less liver background in all but one FDG study. In the left anterior oblique 45° view uncorrected global myocardial FDG and stress Tl‐201 counts were similar, but the FDG study had significantly higher peak myocardial to background ratios. Conclusion Assessing regional cardiac FDG uptake and myocardial perfusion seems feasible with conventional gamma camera technology, providing a widely available and cost effective means of detecting hiber‐nating myocardium. Similar equipment may appreciably reduce the need for positron emission tomography in a range of clinical conditions.