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New Horizons in the Treatment of Multiple Sclerosis
Author(s) -
Heard Robert N S
Publication year - 1993
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1993.tb121925.x
Subject(s) - multiple sclerosis , medicine , neuroscience , clinical trial , new horizons , intervention (counseling) , inflammation , immunology , psychology , pathology , psychiatry , engineering , spacecraft , aerospace engineering
Objective To review and discuss novel therapeutic approaches to multiple sclerosis (MS), particularly strategies designed to modulate immunopathogenetic mechanisms. Data sources Recent medical and scientific publications and the proceedings of recent conferences in Australia and the United States. Conclusions Clearer understanding of the pathogenetic mechanisms leading to inflammation and demyelination in MS is suggesting new strategies for intervention. Both antigen‐specific and non‐antigen‐specific immunomodulation can be achieved in animal models, and human clinical trials of several new agents can be expected shortly.