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Primary cerebral lymphoma: an association with craniopharyngioma or cadaveric growth hormone therapy?
Author(s) -
Forbes Geoffrey M,
Cohen Alexander K
Publication year - 1992
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1992.tb121603.x
Subject(s) - craniopharyngioma , medicine , cadaveric spasm , radiation therapy , lymphoma , primary central nervous system lymphoma , surgery , radiology
Objectives To present the first case of primary cerebral lymphoma associated with craniopharyngioma or previous cadaveric growth hormone therapy. Clinical features A 22‐year‐old male shop assistant of European descent presented with unilateral uveitis and was found to have a high grade primary cerebral lymphoma. This occurred nine years after successful surgical resection of a craniopharyngioma without the administration of adjuvant radiotherapy. Intervention and outcome There was initial radiological resolution of cerebral lymphoma after cranial irradiation. Recurrence was noted 10 weeks later, resulting in the patient's death. Conclusion The development of primary cerebral lymphoma following a craniopharyngioma is considered most likely a chance occurrence. Cadaveric growth hormone therapy may play a role in the genesis of lymphoma.