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Induction of ovulation with gonadotrophin‐releasing hormone — life‐table analysis of 50 courses of treatment
Author(s) -
Kovacs Gabor T.,
Phillips Sharon,
Healy David L.,
Burger Henry G.
Publication year - 1989
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1989.tb128448.x
Subject(s) - ovulation , ovulation induction , medicine , pulsatile flow , pregnancy , hormone , pregnancy rate , gonadotropin releasing hormone , gynecology , endocrinology , luteinizing hormone , biology , genetics
Ovulation induction by means of the pulsatile subcutaneous administration of gonadotrophin‐releasing hormone by way of an infusion pump is described. The clinical outcome in 50 courses of treatment, which totalled 116 treatment cycles, was analysed and was compared with the pregnancy rates that were obtained with the administration of human pituitary gonadotropins. We found that the pregnancy rates for these two treatments were similar. We also have shown that for those women who ovulated as a result of such treatment the conception rates were similar to those in ovulatory women who had discontinued contraception. We conclude that gonadotrophin‐releasing hormone has an important place among the ovulation‐induction agents.