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Presence of antibodies to human immunodeficiency virus‐1 in reference reagents of human origin in diagnostic kits
Author(s) -
Brake Felicity A.,
Breschkin Alan M.,
Gandhi Sunil S.,
Maskill William J.,
Howard Teresa S.
Publication year - 1988
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1988.tb99458.x
Subject(s) - human immunodeficiency virus (hiv) , antibody , virology , reagent , virus , biology , immunology , medicine , chemistry
We tested 54 reagents of human origin that were included in a number of diagnostic kits to be used as positive or negative control material, and for quality assurance, for the presence of antibodies to human immunodeficiency virus‐1 (HIV‐1). Of these, 12 (22%) reagents were found to give positive results for antibodies to HIV‐1 by enzyme‐linked immunosorbent assay and/or supplementary tests. These results suggest that some diagnostic reagents of human origin may be contaminated with HIV‐1 and potentially may be infectious.