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Haemorrhagic fever with renal syndrome involving the liver
Author(s) -
Chan Yow Cheong,
Wong Tze Wai,
Yap Eu Hian,
Tan Hwee Cheng,
Lee Ho Wang,
Chu Yong Kyu,
Lee Pyung Woo
Publication year - 1987
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1987.tb133422.x
Subject(s) - medicine , petechial rash , rash , serology , hepatitis , hantavirus , gastroenterology , disease , pathology , antibody , immunology , virus , surgery
A case of haemorrhagic fever with renal syndrome that originated in Malaysia is reported. The patient presented with clinical symptoms which were not typical of the disease as seen in endemic regions. Renal involvement, which is characteristic of haemorrhagic fever with renal syndrome, was mild, and the predominant symptom was a persistently marked elevation of serum transaminase levels that was suggestive of hepatitis. Liver involvement has not been described in the Asian form of haemorrhagic fever with renal syndrome. The patient developed a petechial skin rash and had severe thrombocytopenia. Serological confirmation of the diagnosis of haemorrhagic fever with renal syndrome was obtained by the demonstration of significant antibody rises to hantaviruses in the patient's acute‐ and convalescent‐phase sera.