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Medulloblastoma: A clinicopathological study of 42 cases
Author(s) -
Ojeda Victor J.,
Armstrong Bruce K.,
Lee Michael A,
Papadimitriou John M.,
Shepherd John M.,
Stokes Bryant AR.,
Thomas G. Wayne,
Cullity Garrett J.,
Jacobsen Phillip F.,
Kakulas Byron A
Publication year - 1985
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1985.tb122798.x
Subject(s) - medulloblastoma , medicine , radiation therapy , meninges , surgery , posterior fossa , fossa , meningioma , pathology , cancer research
collected for 42 patients with cerebellar medulloblastoma diagnosed and treated in Western Australia between the years 1961 and 1984. Thirty‐one patients were male and 12 were over 14 years of age. In 31 patients the neoplasms were localized to the midline, while in 10 they were placed laterally in the cerebellar hemispheres. The remaining patient had a diffusely spreading neoplasm in the meninges of the posterior fossa. Thirty‐nine underwent surgical treatment followed by postoperative radiotherapy. Three patients died in the early postoperative period. Twenty‐four patients survived for one year or longer, 15 for two or more years, 10 for five years, and five survived longer than 10 years. The survival proportions estimated by the life‐table method were 66% at one year, 48% at two years and 32% at 5 and 10 years. In one patient who survived for 23 years a meningioma developed, possibly due to radiotherapy.