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Properties of methicillin‐resistant staphylococci now endemic in Australia
Author(s) -
Gedney Jill,
Lacey Richard W.
Publication year - 1982
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1982.tb132412.x
Subject(s) - cloxacillin , flucloxacillin , staphylococcus aureus , microbiology and biotechnology , staphylococcus , staphylococcal infections , meticillin , biology , medicine , antibiotics , micrococcaceae , penicillin , antibacterial agent , bacteria , genetics
Seventy‐eight cultures of multiresistant Staphylococcus aureus (MRSA), obtained from Australian hospitals in 1981, were studied to see whether they possessed novel properties responsible for their epidemic spread. In general, these strains resembled MRSA from other countries and were probably derived from them; in particular, they did not survive desiccation better than other staphylococci. The majority of MRSA produced lipases, which might be responsible for their invasiveness, and all produced high amounts of /Mactamase which hydrolysed each of the isoxazolyl penicillins. This may account for therapeutic failure with cloxacillin or flucloxacillin. Control of this epidemic should rely principally on general measures against the hospital staphylococcus.