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CORYNEBACTERIUM VAGINALE IN NON‐PURULENT VAGINITIS
Author(s) -
Goei S. H.,
Wells J. I.
Publication year - 1981
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1981.tb135738.x
Subject(s) - vaginitis , medicine , leukorrhea , dermatology , gynecology , pathology , alternative medicine
The diagnostic importance of a cytological evaluation of a Gram‐stained smear of the discharge from a case of non‐purulent vaginitis (NVP) due to Corynebacterium vaginale is emphasized. A battery of rapid laboratory tests designed to identify the organism on the second day of incubation with an accuracy of at least 97% is proposed. In a prospective study of 1402 patients. 310 (22%) were found to be asymptomatic carriers of C. vaginale and 42 (3%) had vaginal discharge attributable only to C. vaginale. The clinical features of NVP and results of several treatment regimens in a controlled trial of treatment are compared. Metronidazole given by mouth (1200 mg/day in divided doses) produced the best remission rate, although complicating candidiasis developed in 25% of cases.