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BODY WEIGHT AND DIETARY FACTORS IN HUNTINGTON'S DISEASE PATIENTS COMPARED WITH MATCHED CONTROLS
Author(s) -
Sanberg Paul R.,
Fibiger Hans C.,
Mark Richard F.
Publication year - 1981
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1981.tb135681.x
Subject(s) - huntington's disease , disease , body weight , medicine , weight gain , weight control , weight loss , medical record , pediatrics , gastroenterology , physiology , obesity
A longitudinal study using medical records has confirmed that, even when eating high energy diets, loss of body weight is characteristic of Huntington's disease patients in comparison with a group of matched control subjects. Further analysis showed that although some Huntington's disease patients initially may gain weight rapidly after a period in hospital, they eventually lose weight to below their admission levels. This pattern was not seen in the control group. The findings are discussed in terms of striatal pathology.